Symposium

Title Poster First Author Abstract or summary Type
Helping young people with psychosis back into education and work: how much progress has been made in realising the goals of the Meaningful Lives International Consensus statement (iFEVR 2008)? Jo Smith

Background: Supporting young people to achieve educational qualifications and secure employment is critical to longer term functional, social and health outcomes and should be a core component of EI service interventions.

Conference Presentations
Intervention development for cannabis dependence in the early phase of psychosis: Creating consensus amongst local, national and international experts using a modified Delphi Method Kevin Madigan

BackgroundSubstance use is recognised as the most common co morbidity of psychosis, with cannabis the substance used most often. A recent 5 year follow-up study of individuals with a first episode psychosis demonstrated that those who continued to use cannabis experienced more psychotic symptoms and poorer functioning. Thirty two Randomised Controlled Trials have failed to support evidence for an effective intervention to improve outcomes, most experiencing difficulties in recruitment and engagement.

Conference Presentations
Mortality attributable to alcohol and substance use disorders in people with schizophrenia Carsten Rygaard Hjorthøj

IntroductionPeople with schizophrenia have higher rates of misuse of alcohol, cannabis, and other illicit substances than the background population. They are also at severely increased risk of early death. The association between substance use and mortality in schizophrenia, however, is not well-established.MethodsWe linked nationwide Danish registers for people born in Denmark from 1955 onwards.

Conference Presentations
Effect of comorbid Cannabis use on risk of readmission in first-episode psychosis: data from two cohorts employing complementary methodology. Sagnik Bhattacharyya

Use of cannabis, the most commonly used illicit drug worldwide, has been linked to increased risk of relapse of illness in patients with psychosis who continue to use the drug. However, most studies investigating the effect of cannabis use on outcome are limited by, either a small sample size, short follow-up duration or outcome measures that rely on change of symptom severity.

Conference Presentations
Autoantibodies in Autoimmune Neuropsychiatric Disorders and Early Psychosis Fabienne Brilot

Recently, autoantibodies have been detected in defined treatable forms of autoimmune encephalitic disorders. Targets of these autoantibodies are neuronal surface receptors or synaptic proteins essential to brain physiology, such as N-Methyl D-Aspartate Receptor (NMDAR), or Dopamine-2 Receptor (D2R). These autoantibodies usually target extracellular domains and are generally detected in patients benefiting from immunosuppressive therapies.

Conference Presentations
Anti-NMDA-receptor Antibodies Detected in Limbic Encephalitis, Schizophrenia and Narcolepsy with Psychotic Symptoms Takashi Kanbayashi

Introduction: Causative role of encephalitis in major psychotic features, dyskinesias (particularly orofacial), seizures, and autonomic and respiratory changes has been recently emphasized. These symptoms often occur in young females with ovarian teratomas and are frequently associated with serum and CSF autoantibodies to the NMDA receptor (NMDAR).Methods: The study included a total of 147 patients from age 12 to 72 and was carried out between Jan 1, 2005, and Dec 31, 2013. The patients were divided into the following three clinical groups for comparison.

Conference Presentations
Transdiagnostic Exploration of the Association of Toxoplasma gondii with Psychiatric Disorders. A Systematic Review and Meta-analysis. Arjen Sutterland

Many studies have investigated the association between Toxoplasma gondii (T. gondii) and schizophrenia. An updated meta-analysis in 2012 showed a significant Odds Ratio (OR) of 2.7. Currently, several studies have looked at the association between T. gondii and other psychiatric disorders as well, rendering exploration of diagnostic specificity possible.

Conference Presentations
Identification of Subgroups of Schizophrenia Patients With Changes in Either Immune or Growth Factor and Hormonal Pathways. Nico van Beveren

Schizophrenia is a heterogeneous disorder normally diagnosed using the Diagnostic and Statistical Manual of Mental Disorders criteria. However, these criteria do not necessarily reflect differences in underlying molecular abnormalities of the disorder. Here, we have used multiplexed immunoassay analyses to measure immune molecules, growth factors, and hormones important to schizophrenia in acutely ill antipsychotic-naive patients (n = 180) and matched controls (n = 398).

Conference Presentations
Psychosocial Intervention: Promoting functional recovery in adult patients with early psychosis: A recovery-oriented life coaching intervention NKM Lau

Disruptions in functioning are commonly reported in patients with psychosis. Apart from symptomatic remission, functioning is one of the most important indicators of recovery. Recent studies have consistently revealed that achievement of adequate functioning is a critical element signifying recovery. Although the majority of first-episode psychosis (FEP) patients achieve symptomatic remission after adequate antipsychotic treatment, a significant proportion of them still exhibit prominent functional impairment.

Conference Presentations
Case Management at the Early Psychosis Prevention and Intervention Centre, Melbourne, Australia: The CBCM Model Craig A Macneil

Case management has been described as the central pillar of early psychosis services, providing clients and their families with a lead clinician who will oversee treatment, undertake therapeutic interventions, offer continuity of care, and provide advocacy. This presentation will focus on the model of case management that is being utilised by the multi-disciplinary team at the Early Psychosis Prevention and Intervention Centre, Melbourne, Australia.

Conference Presentations

Pages