Symposium

Title Poster First Author Abstract or summary Type
Ten-Year Outcomes of Psychotic Disorders: the ÆSOP-10 Study Peter Jones

Background: Schizophrenia was originally conceived as a eteriorating disorder but the broader group of psychotic illnesses may have a wide range of outcomes.Objective: To describe the ten-year outcome of a cohort with first-episode psychosis.Method: We followed-up at ten years the ÆSOP cohort, 557 subjects with a first-episode of psychosis identified in two geographically defined areas of the UK during the late 1990s.Results: Thirty nine (7.0%) cases had died, the majority through unnatural means.

Conference Presentations
Making the Case for Early Intervention Peter Jones

Getting on the same page?

Conference Presentations
Clinical, Neurocognitive, and Neuroimaging Characteristics of adolescent Bipolar and Schizophrenia Offspring Manon H. J. Hillegers

Background: Bipolar disorder and schizophrenia are severe neuropsychiatric disorders. Several authors have defended the notion that schizophrenia and bipolar disorders should be studied jointly, given that they have common clinical, genetic and cognitive characteristics (Craddock et al, 2006). To our knowledge, only one study to date has jointly analysed child and adolescent offspring of schizophrenia and bipolar disorder patients employing DSM-IV criteria (Maziade et al, 2008).

Conference Presentations
Implications of Developmental Impairments for Early Interventions to Prevent Psychosis Larry Seidman

Background: Intervention strategies for reducing disability and preventing psychotic disorders have evolved from First Episode to Ultra-High Risk to earlier phases of pre-psychotic illness. Which potential intervention targets are highlighted by familial high-risk (FHR) studies? Methods: Results from our 2 recent quantitative and qualitative reviews on neurocognition and brain imaging (MRI) in youth at FHR for psychosis, and results of three of our own studies characterizing youth at FHR will be summarized, focusing on neurocognition and behavior from the prenatal period to age 25.

Conference Presentations
Screening strategies to identify individuals at high risk of developing a bipolar disorder JAN SCOTT

Bechdolf and colleagues, recently developed a BD 'at-risk (BAR) assessment tool for use with help-seeking individuals. The BAR assessment incorporates general criteria and specific criteria, such as: cyclothymia, sub-threshold mania, depression and genetic risk. Utilisation of these criteria in early intervention services have produced promising findings.

Conference Presentations
THE PREDICTIVE VALIDITY OF BIPOLAR AT-RISK (PRODROMAL) CRITERIA IN HELP SEEKING ADOLESCENTS AND YOUNG ADULTS: A PROSPECTIVE STUDY ANDREAS BECHDOLF

There are no established tools to identify individuals at risk for developing bipolar disorder. We developed a set of risk criteria for bipolar affective disorder (bipolar at-risk - BAR). And tested their predictive validity in a 12-month prospective study that was conducted at Orygen Youth Health Clinical Program (OYH).At intake, BAR screen-positive individuals and a matched group of individuals who did not meet BAR criteria were observed over a period of 12 months.

Conference Presentations
Clinical Staging Models and Risk of Bipolar Disorder IAN HICKIE

A major challenge for early intervention psychiatry is to identify those persons who are at increased risk of developing recurrent unipolar or bipolar mood disorders, assuming that such identification will lead to interventions that reduce poor long-term outcomesThis paper will report on subjects attending novel headspace services for young persons with emerging major mental disorders are followed longitudinally, with subsets recruited for more detailed neurobiological studies.

Conference Presentations
Clinical Staging of Major Depressive Disorder: an empirical exploration JUDITH VERDUIJN

We examined the construct and predictive validity of a clinical staging model for major depression that distinguishes eight consecutive stages (0,1A,1B,2,3A,3B,3C,4) based on severity and duration of symptoms, and number of episodes. At baseline 2334 Netherlands Study of Depression and Anxiety participants were assigned to the eight stages of the model, of them 2012 were followed-up after 2 years. For construct validity, differences between stages in clinical characteristics (e.g.: severity, age of onset, co-morbid anxiety) were studied.

Conference Presentations
Mapping developments in the provisionof early intervention services: economic and health policy perspective David McDaid

no abstract available

Conference Presentations
Measuring fidelity in a National First Episode Psychosis System Eoin Killackey

no abstract available

Conference Presentations

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