Trajectories of Negative Symptoms Following a First Episode of Psychosis and Implications for Social and Functional Recovery

Presentation First Author: 
Jo Hodgekins

Negative symptoms are not a stable trait but are subject to significant fluctuations over time. Individuals vary in the stability of their negative symptoms and those with persistently elevated negative symptoms are at highest risk of poor long term outcome. Research investigating individual trajectories of negative symptoms early in the course of non-affective psychosis is limited and little is understood about the longitudinal interplay of negative symptoms and social recovery. The aim of this study was to explore differing trajectories of negative symptoms using longitudinal data from a cohort of individuals receiving treatment for a first psychotic episode. Latent Class Growth Analysis (LCGA) was used to analyse change in negative symptoms and social functioning over a 12 month period using data from the National EDEN study. Persistent negative symptoms were present in a small group of individuals. However, poor social recovery outcomes were more common; suggesting that negative symptoms only partially explain delayed social recovery. Predictors of persistent negative symptoms were examined and implications for assessment and psychosocial interventions are discussed in the context of a current randomised controlled trial.

Conference Name: 
Presentation Date: 
January, 2015
Additional Authors: 
Brioney Gee - Max Birchwood - Max Marshall - Peter Jones - Swaran Singh - David Fowler
See other presentations in this session: