Ten-Year Outcomes of Psychotic Disorders: the ÆSOP-10 Study

Presentation First Author: 
Peter Jones

Background: Schizophrenia was originally conceived as a eteriorating disorder but the broader group of psychotic illnesses may have a wide range of outcomes.Objective: To describe the ten-year outcome of a cohort with first-episode psychosis.Method: We followed-up at ten years the ÆSOP cohort, 557 subjects with a first-episode of psychosis identified in two geographically defined areas of the UK during the late 1990s.Results: Thirty nine (7.0%) cases had died, the majority through unnatural means. Thirty (5.4%) had emigrated, and 8 (1%) were excluded; information on follow up was collated for 394 (82%) of the remaining 480. Most (270, 77%) experienced at least one period of remission but the majority (211, 71%) had been unemployed for more than 75% of the follow-up period. Overall, outcomes were worse for men and those with a non-affective diagnosis.Conclusions: The overall symptomatic course of psychoses may be better than previously thought, but social outcomes in 21st century UK are disappointing.

Conference Name: 
Presentation Date: 
January, 2015
Additional Authors: 
C Morgan - J Lappin - H Heslin - K Donoughue - B Lomas - U Reininghaus - A Onyejiaka - T Croudace - Robin Murray - P Fearon - P Dazzan
See other presentations in this session: