Shortening the duration of untreated psychosis: experiences from the tips study.

Presentation First Author: 
Ingrid Melle

The Scandinavian “Early Treatment and Intervention in Psychosis” (TIPS) study use a multifocused approach consisting of mass-media campaigns combined with focused education of key personnel (GPs, school nurses, teachers) and low-threshold assessment teams to recruit patients with first episode psychosis (FEP). The study included consecutive FEP from four Scandinavian health care sectors, half with the early detection program (ED) and half without (NoED). At start of first treatment, patients from the ED area had a statistically significantly shorter duration of untreated psychosis. ED area patients also had statistically significantly lower symptom levels across all symptom dimensions and significantly lower prevalence of severe suicidal behavior; attributed to the shortening of the DUP. Significant differences in negative symptoms were maintained at the one, two and five year follow-up, and patients from the ED area were more likely to be recovered after ten years in treatment. The focused information program and the low threshold teams were continued after the study period while the information campaigns were preliminary stopped and this was followed by an increase in DUP. Reinstating the campaigns led to a second decrease in DUP, emphasizing the role of mass media campaigns for DUP reducing strategies.

Conference Name: 
Presentation Date: 
January, 2013
Additional Authors: 
Ingrid Melle, Inge Joa, TK Larsen, Ulrik Haahr, Svein Friis, Jan Olav Johannesen, Stein Opjordsmoen, Erik Simonsen, Per Vaglum, Tom McGlashan
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