Public health significance of bipolar disorder: implications for early intervention and prevention

Presentation First Author: 
Philippe Conus

Objectives: Early intervention and preventive strategies have become major targets of research and service development in psychiatry over the last few years. Compared to schizophrenia, bipolar disorder (BD) has however received limited attention in this regard. In a review of the available literature, we explored the public health significance of BD and the extent to which this may justify the development of early intervention strategies for this disorder. Methods: The main computerized psychiatric literature databases were accessed. This included Medline and PsychInfo, using the following keywords: Bipolar, Early Intervention, Staging Model, Burden, Caregiver, Public Health, and Manic Depression. Results: BD is often recurrent and has an impact that goes well beyond symptomatic pathology. The burden it incurs is linked to its cardinal clinical features, as well as to cognitive dysfunction, poor functional outcome, poor physical health, high rate of co morbidities and suicide. At a societal level, BD induces enormous direct and indirect costs and has a major impact on caregivers. Current literature reveals a usually long delay between illness onset and start of treatment and the absence of specific guidelines for the treatment of the early phase of BD. Conclusions: Considering the major impact BD has on patients and society, there is an urgent need for the development of early intervention strategies aimed at earlier detection and more specific treatment of the early phase of the disorder.

Conference Name: 
Presentation Date: 
January, 2015
Additional Authors: 
Craig Macneil - Patrick McGorry
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