Early Lifestyle Intervention Attenuates Antipsychotic-Induced Weight Gain In First Episode Psychosis

Presentation First Author: 
Jackie Curtis

Youth with first episode psychosis (FEP) receiving antipsychotic (AP) medications are at risk of obesity and metabolic syndrome. AP initiation induces rapid deterioration in metabolic health, with up to 77% experiencing clinically significant (>7%) weight-gain within 12 months(1,2). We aimed to determine whether a multidisciplinary, 12-week intervention could attenuate weight gain. Young people with FEP aged 15-25 were enrolled in the 'Keeping the Body in Mind Program, including weekly individualized dietetic monitoring and education and group education, and individualized exercise prescriptions by an exercise physiologist, utilising a supervised on-site gym. Controls were youth with FEP from another service that did not offer lifestyle interventions. 16 participants (56% females, mean age 20.0 ± 2.3) years) completed the intervention, and data were obtained from 12 controls (8% female, mean age 21.7 ± 2.0). Weight gain was substantially lower in the intervention group compared to controls (1.8kgs ± 3.0 versus 7.8kgs ± 4.7, p

Conference Name: 
Presentation Date: 
January, 2015
Additional Authors: 
Andrew Watkins - Simon Rosenbaum - Scott Teasdale - Megan Kalucy - Katherine Samaras - Philip B. Ward
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