Early Lifestyle Intervention Attenuates Antipsychotic-Induced Weight Gain In First Episode Psychosis

 
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Presentation First Author: 
Jackie Curtis
Abstract: 

Youth with first episode psychosis (FEP) receiving antipsychotic (AP) medications are at risk of obesity and metabolic syndrome. AP initiation induces rapid deterioration in metabolic health, with up to 77% experiencing clinically significant (>7%) weight-gain within 12 months(1,2). We aimed to determine whether a multidisciplinary, 12-week intervention could attenuate weight gain. Young people with FEP aged 15-25 were enrolled in the 'Keeping the Body in Mind Program, including weekly individualized dietetic monitoring and education and group education, and individualized exercise prescriptions by an exercise physiologist, utilising a supervised on-site gym. Controls were youth with FEP from another service that did not offer lifestyle interventions. 16 participants (56% females, mean age 20.0 ± 2.3) years) completed the intervention, and data were obtained from 12 controls (8% female, mean age 21.7 ± 2.0). Weight gain was substantially lower in the intervention group compared to controls (1.8kgs ± 3.0 versus 7.8kgs ± 4.7, p

Conference Name: 
Presentation Date: 
January, 2015
Additional Authors: 
Andrew Watkins - Simon Rosenbaum - Scott Teasdale - Megan Kalucy - Katherine Samaras - Philip B. Ward
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