Does individual placement and support compensate for neurocognitive deficit in first-episode psychosis?

Presentation First Author: 
Kelly A Allott

Neurocognitive deficit, a hallmark of psychotic disorder, is associated with poorer vocational outcomes. Individual Placement and Support (IPS) is effective at improving vocational outcomes for people with psychosis. It has been proposed that IPS may function to compensate for neurocognitive deficits. This study will test the hypothesis that IPS compensates for the neurocognitive difficulties experienced by people with first-episode psychosis (FEP). Specifically, it aims to determine: a) whether hours of IPS service are related to level of neurocognition; and b) whether neurocognition moderates the relationship between IPS hours and vocational outcome. A total of 146 FEP participants were randomised to receive either 6 months of IPS plus treatment as usual (TAU) or TAU (n=73 in both groups). The current study includes the participants who were in the IPS plus TAU arm and seen by the IPS worker (n=69). At baseline participants completed a comprehensive neurocognitive battery. Preliminary results indicate that over a period of 6 months, the IPS clinician provided a mean of 22.2 hours of IPS per participant (SD=14.8, range 4.3 to 83.8 hours). Preliminary Pearson correlations found significant negative relationships (p<.01) between IPS hours and neurocognitive performance. Highest correlations were found on tests of processing speed, verbal learning and memory, divided attention and verbal fluency. Thus, poorer neurocognitive performance was associated with more hours of IPS, providing some support for the tenet that IPS compensates for neurocognitive dysfunction. Whether neurocognition moderates

Conference Name: 
Presentation Date: 
January, 2013
Additional Authors: 
Kelly A Allott, Gina L Chinnery, Susan M Cotton, Henry J Jackson, Eoin J Killackey
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