Basic self-disturbance in the ultra high risk and first episode psychosis populations: Findings from the PACE Clinic

Presentation First Author: 
Barnaby Nelson

Background Phenomenological research indicates that disturbance of the basic sense of self may be a core phenotypic marker of schizophrenia spectrum disorders. This refers to disruption of the implicit sense of ownership of experience and agency and is associated with a variety of dissociative symptoms and anomalous cognitive and bodily experiences. Several studies have been conducted at PACE in order to explore this model in early psychosis populations. Method The first study assessed the predictive utility of a basic self-disturbance measure (the EASE) in a UHR sample (N=49). The second study assessed the relationship between borderline personality pathology and basic self-disturbance in the same UHR sample (N=42). The third study assessed basic self-disturbance in relation to type of psychotic diagnosis in a FEP sample (N=16). Results Basic self-disturbance scores were significantly higher in the UHR sample compared to a healthy control group (p<.001 and="" predicted="" transition="" to="" psychotic="" disorder="" over="" a="" year="" follow-up="" period="" no="" correlation="" was="" found="" between="" basic="" self-disturbance="" borderline="" personality="" pathology.="" in="" the="" fep="" sample="" scores="" were="" significantly="" higher="" schizophrenia="" spectrum="" cases="" compared="" other="" diagnoses.="" discussion="" results="" indicate="" that="" identifying="" uhr="" patients="" may="" provide="" means="" of="" further="" closing="" on="" true="" positive="" cases.="" findings="" are="" consistent="" with="" model="" different="" types="" characterise="" disturbance="" selfhood="" is="" phenotypic="" marker="" rather="" than="" psychosis="" more="" broadly.="">

Conference Name: 
Presentation Date: 
January, 2015
Additional Authors: 
Andrew Thomson - Alison - R. Yung
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