IEPA 2014

Title Poster First Author Abstract or summary Type
Certain cannabis compounds make cannabis less harmful. Amir Englund

It is well established that heavy long-term cannabis use, particularly which starts at a young age, significantly increases the risk of cognitive impairment, psychosis, as well as hastens the onset of psychosis. However, cannabis consists of over 85 cannabis specific compounds known as cannabinoids, each of which with difference pharmacological effects. ∆9-tetrahydrocannabinol (THC) is the main cannabinoid and also responsible for the negative effects of cannabis when taken in high doses.

Conference Presentations
Cannabis use as a predictor for relapse in First Episode Psychosis: A three-year follow up study Tabea Schoeler

Background. The emergence of a relapse following a first episode psychosis (FEP) is common in patients suffering from the disorder. Although cannabis represents one potential factor that predicts relapse, conclusions from current findings are limited given the cross-sectional nature of study designs and the inclusion of patients that are at different stages of their illness. Methods. Ninety-five FEP participants presenting to an inner city service in London were assessed at follow-up.

Conference Presentations
Facial emotion identification in early-onset psychosis Sophie Barkl

Facial emotion identification (FEI) deficits are common in patients with chronic schizophrenia and are strongly related to impaired functioning. The objectives of this study were to determine whether FEI deficits are present and emotion specific in people experiencing early-onset psychosis (EOP), and related to current clinical symptoms and functioning. Patients with EOP (n = 34, mean age = 14.11, 53% female) and healthy controls (HC, n = 42, mean age 13.80, 51% female) completed a task of FEI that measured accuracy, error pattern and response time.

Conference Presentations
Interventions to prevent suicidal behaviour in individuals with psychotic disorder Merete Nordentoft

Introduction: Suicide rates among people with psychotic disorders are 20 fold higher than among people in the general population. Methods and results: Meta analyses of suicide risk in schizophrenia are mentioned and risk factors for suicide in schizophrenia are reviewed. Danish population registers were used to determine a long term cumulated risk of suicide of four percent for women and six percent for men. Two high risk periods for suicide were identified: shortly after admission and shortly after discharge.

Conference Presentations
Cost and Effect of Early Intervention on admission in First Episode Psychosis Caragh Behan

Early intervention in psychosis (EIP) is an accepted policy internationally. It is necessary to evaluate whether policies are applicable within a local context. In Ireland in 2012 the National Clinical Programme Plan identified EIP as one of three priorities for development. Concurrently the health budget has been reduced, highlighting the need for economic evaluation of all new initiatives. Admission is an outcome however it is also a large proportion of the direct cost.

Conference Presentations
Calgary Fidelity Scale for First Episode Psychosis Services (CFEPS) Donald Addington

Purpose: The purpose of this study was to develop a fidelity scale to assess the degree of implementation of essential evidence-based components for First Episode Psychosis Services (FEPS). Methods: We used a 3 stage knowledge synthesis process: a systematic review of the literature in order to identify service components; a DELPHI consensus-building technique with an international panel of experts; and a construction and pilot testing phase. Results: The literature review identified 1,020 citations, from which 280 peer reviewed articles met criteria for relevance.

Conference Presentations
Debate: Early Intervention for all mental disorders in all age groups would compromise the gains of decades of EI Psychosis Teams Peter Byrne

Early Intervention (EI) for young people with psychosis has become the gold standard. Generic community mental health services have too many other demands made of them to deliver specialist EI to this or other groups. They provide lifetime care to people with severe mental disorders (SMI) and are the gatekeepers for new onset disorders, provided patients' symptoms reach the threshold of severity and duration. Lowering this threshold or holding cases that may not develop SMI would overwhelm services so that no group would receive adequate levels of care.

Conference Presentations
Predictors of caregiver distress in first-episode psychosis: subjective appraisal and expressed emotion Jens Einar Jansen

Background: Caregivers of persons with first-episode psychosis (FEP) often report high levels of distress. Preventing long-term or chronic distress within the whole family is an important focus of early intervention for psychosis. However, little is known about the psychological factors involved. Aims: To examine the impact of subjective appraisals and expressed emotion on caregiver distress in FEP.

Conference Presentations
Life after Early Intervention for Psychosis Services –What happens once the doors close? Linda Everard

Background: Little is known about patients service trajectories once discharged from high intensity Early Intervention teams to lower intensity services such as Community Mental Health Teams (CMHTs) or GPs. We sought to investigate where clients are discharged to, whether they remain free from mental health service input and how many bounce between primary and secondary care 2 years post EIS. Method: The authors studied 1027 young adults with first episode psychosis.

Conference Presentations
Longer-term follow-up in the Vienna omega-3 psychosis prevention trial G. Paul Amminger

Background: We have shown that a 12-week intervention with long-chain omega-3 polyunsaturated fatty acids (PUFAs) reduced the risk of progression to psychotic disorder in young people with subthreshold psychotic states for a 12-month period (Amminger et al., 2010, Arch Gen Psychiatry). Now we have completed a longer-term follow-up of this trial to determine the longer-term efficacy of omega-3-PUFAs in individuals at ultra-high risk (UHR) for psychosis. Methods: Randomized, double-blind trial of 1.2g/day omega-3 PUFAs or placebo in 81 UHR individuals.

Conference Presentations

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