IEPA 2014

Title Poster First Author Abstract or summary Type
Early Psychosis Intervention in an Asian Context: a decade of Real-life developments and outcomes in Hong Kong. Eric Chen

Early Intervention Programs worldwide are guided by a set of common frameworks. They include early detection through reduction of duration of untreated psychosis, provision of phase specific intervention to optimise outcomes in the critical period, as well as prevention before full-blown psychosis. Early psychosis programs worldwide implement these objectives in diverse real-life cultural and service settings. The interaction between ideas and implementation shaped the eventual form and outcome of services.

Conference Presentations
Preventive Strategies in Emerging Mental Disorders in Young People: Clinical Staging and Translational Research Patrick D. McGorry

A key goal in psychiatry is to build new diagnostic, therapeutic and translational tools and capacity to reduce the impact of emerging mental disorders in young people on survival, distress, quality of life and productivity. Young people bear the major burden of onset for mental disorders with 75% of such illnesses appearing before age 25 years. This can only be done within a novel non-stigmatising interface between young people and clinical care in mental health such as that recently created by headspace in Australia and increasingly in some other developed nations.

Conference Presentations
The At-Risk Mental State: An Inflammatory Reformulation of Mind and Body Peter B. Jones MSc

The at-risk mental state has been an important concept in early intervention: a call to arms before a diagnosis is clear and disability has crystallised. However, it has not been without controversy as the debates regarding inclusion of a related category in DSM-5 have shown. Whether the at-risk mental state is a discrete entity presaging a single, psychotic outcome or is better seen as a particular view of a more dimensional concept remains unclear.

Conference Presentations
Cognitive Enhancement and Illness Management and Recovery in Vocational Rehabilitation Susan R. McGurk

The Thinking Skills for Work program (TSW) is a combined cognitive remediation and vocational rehabilitation (VR) program that incorporates restorative tasks practice and compensatory strategies to improve cognitive functioning and optimize work functioning. Five randomized controlled trials comparing TSW + VR vs. VR alone have shown that clients in TSW improved more in cognition than clients who received VR alone and had better work outcomes over a 18-36 months follow up.

Conference Presentations
Recovery after an initial Schizophrenia episode (RAISE): Early Treatment Program (ETP) John M. Kane

The RAISE-ETP program was designed to develop and evaluate an integrated treatment for first episode psychosis (NAVIGATE) in real world, non-academic, community treatment sites in the USA We selected 34 clinics, located in 21 states, and randomized the sites (clusters), rather than individuals, to either implement NAVIGATE or to provide customary Community Care for subjects in the study. Cluster randomization insured that clinicians at Community Care sites were not exposed to NAVIGATE in order to avoid spillover/contamination effects.

Conference Presentations
The RAISE ETP Study: Initial Results John M. Kane

The RAISE-ETP program was designed to develop and evaluate an integrated treatment for first episode psychosis (NAVIGATE) in real world, non-academic, community treatment sites in the USA We selected 34 clinics, located in 21 states, and randomized the sites (clusters), rather than individuals, to either implement NAVIGATE or to provide customary Community Care for subjects in the study. Cluster randomization insured that clinicians at Community Care sites were not exposed to NAVIGATE in order to avoid spillover/contamination effects.

Conference Presentations
Abnormal resting Cerebral Blood Flow (rCBF) reflects change in functioning in subjects at Ultra High Risk for Psychosis Paul Allen

Continuous Arterial Spin Labeling (cASL) is an MR perfusion technique suitable for translational applications as the associated scanning protocols are relatively simple and short. The aim of the study was to investigate whether resting cerebral blood flow (rCBF), measured with cASL, is altered in individuals at ultra high-risk (UHR) of psychosis and whether rCBF is sensitive to longitudinal clinical change in an UHR group. cASL imaging was used to measure rCBF in 52 individuals at UHR of psychosis and 30 healthy control participants.

Conference Presentations
Possibilities for intervention in the early phases of psychoses Merete Nordentoft

The early phase of psychosis is the most vulnerable phase with high risk of suicidal acts and social marginalisation.The evidence for the effectiveness of specialized assertive early intervention services is mainly based on the OPUS trial, but it is supported by the findings in smaller trials such as the LEO trial, the COAST-trial and the Norwegian site of Optimal Treatment trial (OTP). There are positive effects on psychotic and negative symptoms, on substance abuse and user satisfaction, but the clinical effects are not sustainable when patients are transferred to standard treatment.

Conference Presentations
Screening strategies to identify individuals at high risk of developing a bipolar disorder JAN SCOTT

Bechdolf and colleagues, recently developed a BD 'at-risk (BAR) assessment tool for use with help-seeking individuals. The BAR assessment incorporates general criteria and specific criteria, such as: cyclothymia, sub-threshold mania, depression and genetic risk. Utilisation of these criteria in early intervention services have produced promising findings.

Conference Presentations
Case-management models for early psychosis intervention in Asia Hee Eon Choi

After 5 years from a first episode of schizophrenia, only few patients (13.7~25.5%) are reported to have adequate social function. This findings stress the need to provide phase-specific psychosocial intervention to improve social function during the critical period. In 2010, a community-based psychosocial intervention program, Mind Flower Service, was developed in Jeonju mental health promotion center in collaboration with Chonbuk National University Hospital.

Conference Presentations

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