IEPA 2014

Title Poster First Author Abstract or summary Type
Mapping developments in the provisionof early intervention services: economic and health policy perspective David McDaid

no abstract available

Conference Presentations
Clinical Staging of Major Depressive Disorder: an empirical exploration JUDITH VERDUIJN

We examined the construct and predictive validity of a clinical staging model for major depression that distinguishes eight consecutive stages (0,1A,1B,2,3A,3B,3C,4) based on severity and duration of symptoms, and number of episodes. At baseline 2334 Netherlands Study of Depression and Anxiety participants were assigned to the eight stages of the model, of them 2012 were followed-up after 2 years. For construct validity, differences between stages in clinical characteristics (e.g.: severity, age of onset, co-morbid anxiety) were studied.

Conference Presentations
Clinical Staging Models and Risk of Bipolar Disorder IAN HICKIE

A major challenge for early intervention psychiatry is to identify those persons who are at increased risk of developing recurrent unipolar or bipolar mood disorders, assuming that such identification will lead to interventions that reduce poor long-term outcomesThis paper will report on subjects attending novel headspace services for young persons with emerging major mental disorders are followed longitudinally, with subsets recruited for more detailed neurobiological studies.

Conference Presentations
THE PREDICTIVE VALIDITY OF BIPOLAR AT-RISK (PRODROMAL) CRITERIA IN HELP SEEKING ADOLESCENTS AND YOUNG ADULTS: A PROSPECTIVE STUDY ANDREAS BECHDOLF

There are no established tools to identify individuals at risk for developing bipolar disorder. We developed a set of risk criteria for bipolar affective disorder (bipolar at-risk - BAR). And tested their predictive validity in a 12-month prospective study that was conducted at Orygen Youth Health Clinical Program (OYH).At intake, BAR screen-positive individuals and a matched group of individuals who did not meet BAR criteria were observed over a period of 12 months.

Conference Presentations
Implementing early intervention in Japan: Its challenges and difficulties Masafumi Mizuno

For many years, the reliance on hospital-based psychiatry has been a barrier for the development of community-based psychiatry in Japan and increased stigma against mental illness and people suffering from psychiatric disorders. Even in this adverse situation, some innovative hospitals have attempted to make the transition to community-based psychiatry through their own endeavors.

Conference Presentations
Investigating developmental trajectory of self-regulation and vulnerability to psychosis by neuroimaging: subsample of Tokyo Teen Cohort study Naohiro Okada

Tokyo Teen Cohort (TTC) study is a large-scale general population-based survey to elucidate puberty development during adolescence, especially the acquisition process of self-regulation and willingness to challenge, through focusing on interaction between bio, psycho, and social factors. Participants include 5,000 10-year-old children and their carers living in Tokyo Metropolitan area. Information about characteristics of daily life, family form, physical and mental health, and puberty onset as well as about self-regulation and psychological well-being is acquired from participants.

Conference Presentations
Reduced rostral prefrontal cortex activity is associated with poor functional outcome in ultra-high risk and first-episode psychosis Shinsuke Koike

Longitudinal clinical investigations and biological measurements for psychosis have enabled us to clarify not only progressive brain volumetric and functional changes but also the alternations of developmental pathways based on gene–environment interaction model. However, these studies have little contribution to clinical decisions on differential diagnosis and therapeutic choices. Near-infrared spectroscopy (NIRS) is a relatively small instrument with little noise that can easily and noninvasively measure hemoglobin changes over the surface of the cortex.

Conference Presentations
Neuroimaging in people at high risk for psychosis Philip McGuire

Philip McGuire is Head of the Department of Psychosis Studies at the Institute of Psychiatry, Academic Director and joint Leader of the Psychosis Clinical Academic Group, Kings Health Partners, and Director of OASIS. He is a Fellow of the Academy of Medical Sciences, the Royal College of Psychiatrists, the European Psychiatric Association, and the International College of Neuropsychopharmacology, and Associate Editor of the British Journal of Psychiatry. He studied physiology and medicine at the University of Edinburgh, then worked as a research fellow in neuroscience at Yale University.

Conference Presentations
Predicting psychopathology: What has the familial high risk strategy taught us? Matcheri Keshavan MD

Neurocognitive and neurobiological alterations in schizophrenia (SZ) have been utilized as potential predictive trait markers that may predate the illness and manifest in relatives of patients. Adolescence is the age of maximum vulnerability to the onset of SZ and may be an opportune window to observe such biobehavioral changes close to but prior to the onset of psychosis. I will review the extant studies assessing premorbid alterations in young relatives at high risk (HR) for SZ.

Conference Presentations
Translating the philosophy of early intervention to clinical and research practice in bipolar disorders: Looking for a haystack! Jan Scott

The clinical and research models promoted by the 'early intervention movement have transformed strategic approaches to the early stages of psychosis. This talk will explore whether this approach can be utilized in mood disorders in general, and in bipolar disorders in particular.

Conference Presentations

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