IEPA 2014

Title Poster First Author Abstract or summary Type
Does A Prodrome Exist in Bipolar Disorder? Christoph U Correll

Background: Despite therapeutic advances, bipolar disorder (BD) remains one of the most debilitating psychiatric disorders. Unfortunately, lacking knowledge about the underlying pathophysiology limit early identification and indicated prevention efforts. Therefore, early characterization of the prodromal (subsyndromal) stages of BD has attracted increasing attention, especially in youth, given the early age of first BD symptom onset.

Conference Presentations
Developing Strategies to Reduce DUP in the Age of Social Media and the Internet John M Kane

Background:Despite the severity of first episode of psychosis (FEP), the duration of untreated psychosis (DUP) averages 2 years, preceded by another 2 years of prodromal symptoms. Longer DUP independently predicts readmissions, greater symptom severity and poor quality of life. Although FEP individuals are young and use social media and the internet widely, these novel technologies have been leveraged insufficiently to reduce DUP.

Conference Presentations
Screening for early psychosis and risk for psychosis Rachel Loewy

Background: Self-report screening for psychosis and psychotic-like symptoms is an important tool used by early detection efforts to reduce the duration of untreated psychosis (DUP) and to identify youth experiencing clinical high risk for psychosis (CHR). Methods: We will describe a series of validation studies of the Prodromal Questionnaire (PQ) and two brief versions of the measure, tested in a variety of settings in multiple languages and countries: early psychosis clinics, general mental health clinics, university courses, and in a prison population.

Conference Presentations
Phenomenology of psychotic symptoms in borderline personality disorder versus schizophrenia spectrum or affective psychotic disorders: a systematic review Felix-Antoine Berube

OBJECTIVES: There is currently no consensus regarding the phenomenology and severity of hallucinations and other psychotic phenomena associated with Borderline Personality Disorder (BPD). This review investigates the quality, duration, functional impact, distress related to psychotic symptoms occurring in the context of BPD compared with psychotic symptoms occurring in the context of schizophrenia spectrum disorders (SSD) or affective psychotic disorders. It also examines the relations of these symptoms to life-events and dissociative symptoms.

Conference Presentations
A comparison of psychotic symptoms in youth with borderline personality disorder or first-episode psychosis. Andrew Chanen

Objective: To characterise the phenomenology, intensity and functional impact of psychotic experiences in first-presentation BPD patients and to compare these experiences with those from a first episode psychosis (FEP) sample. Methods: A cross-sectional interview was conducted that included the Brief Psychiatric Rating Scale (BPRS) and the Community Assessment of Psychic Experiences (CAPE-_42) scores with four groups of patients: BPD + FEP (n=17), FEP (n=16), BPD (n=34), and clinical controls (n=49).

Conference Presentations
Psychotic symptoms and borderline personality disorder in youth Martina Jovev

DSM-5 criterion 9 for Borderline Personality Disorder (BPD) refers to the presence of transient, stress-related paranoid ideation or severe dissociative symptoms. This criterion suggests possible overlap with first episode psychosis. However, the relationship between psychosis and BPD is neither conceptually clear nor have there been many empirical studies into the treatment, overlap or association between these two disorders. Participants (n=23) were selected from a clinical file audit study conducted at the Helping Young People Early (HYPE) Program in Melbourne, Australia.

Conference Presentations
Brain morphologic changes during the course of schizophrenia Tsutomu Takahashi

Previous MRI studies have demonstrated gross brain morphologic changes, such as altered sulcogyral pattern, at the onset of first-episode schizophrenia, suggesting an early neurodevelopmental disturbance. Recent studies in individuals at ultra high-risk of psychosis (UHR) further supported the neurodevelopmental pathology of schizophrenia. On the other hand, longitudinal MRI studies have demonstrated active progressive brain changes especially in temporal regions during the initial stage of illness, which may represent a pathological process in late neurodevelopment.

Conference Presentations
Prevalence of At-Risk Criteria of Psychosis in Children and Adolescents, and in Young Adults: Results from Two Swiss Community Samples Stephan Ruhrmann

The prevalence and significance of APS and other risk symptoms in the general population, when assessed in the same way as in help-seeking persons, is still rather unclear. In two complimentary studies, we studied the prevalence of ultra-high risk and basic symptom criteria and symptoms assessed with the 'Structured Interview for Psychosis-Risk Syndromes (SIPS) and the 'Schizophrenia Proneness Instrument, Adult / Child and Youth version (SPI-A/SPI-CY) by trained psychologists in random community samples of age 8-17 and 16-40 years.

Conference Presentations
Liberiamo il Futuro: First results of an Italian early detection project Martina Brandizzi

Psychotic-like experiences (PLEs) are commonly endorsed in questionnaires in community and clinical populations, especially by adolescents. Within the early detection project Liberiamo il Futuro (LIF), the prevalence of attenuated psychotic-like experiences (APLEs) in a sample of help-seeking adolescents (11-18 yrs) and the correlation with age, functioning and risk status is explored.

Conference Presentations
Best buys for early intervention to improve cardiometabolic health in adults with psychosis: an Australian perspective Debra L Foley

Those with psychosis are more likely to develop diabetes and to die prematurely from coronary heart disease than those in the general community. There is a pressing need to implement effective interventions that target the earliest expressions of cardiometabolic risk.

Conference Presentations

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