IEPA 2012

Title Poster First Author Abstract or summary Type
Fronto-Striatal Volumes In A Brief Longitudinal Study Of Antipsychotic-Naive First-Episode Psychosis Patients. Donna Lang

Cortico-striatal circuits, form pathways subserving executive functioning, attention, psychomotor co-ordination, and affective attribution, processes which are abnormal in schizophrenia. Subtle to moderate abnormalities of striatal morphology and function have been posited in schizophrenia, even at the first break.

Conference Presentations
Long term follow up of a group at ultra high risk for psychotic disorder: transition to psychosis and functional outcome A.R. Yung

Background Although short to medium term rates of transition to psychosis in Ultra High Risk (UHR) groups are well researched, longer follow up rates are not known. Furthermore, transition to psychosis, defined by positive symptoms, has traditionally been the outcome of interest these studies. In this study we also assessed functional outcome and the relationship between functioning and transition status. Methods We aimed to follow up all previous UHR research participants from the PACE clinic, Melbourne (n=416). Transition to psychosis was determined CAARMS.

Conference Presentations
Reducing DUP in first-episode psychosis requires a detailed understanding of care pathways in community and mental health service settings: data from Birmingham UK Charlotte Connor

This study described in this paper has two aims. First to understand the delays in the care pathway for first episode psychosis in a large multicultural city in the UK. Second, to target these delays in a public health intervention.DUP data from the Birmingham lead site of the National EDEN cohort study were analysed. One third of the sample were identified with a DUP exceeding 6 months, which previous findings suggest is the critical point at which full recovery is impeded.

Conference Presentations
Treating cannabis use disorders in patients with psychosis Carsten R Hjorthoj

To date, a number of studies have attempted to treat cannabis use disorders (or substance use disorders in general) in patients with comorbid mental illness such as psychosis. This presentation will present the results from two systematic reviews on these, as well as from at least four trials on psychosocial interventions conducted or published following these reviews. In particular, focus will be on the CapOpus trial, of which the presenter has been an investigator.

Conference Presentations
Smaller Mismatch Negativity Amplitudes Correlate With Cognitive And Functional Impairments In Young People With ‘At Risk Mental States’. Alana Scully

BACKGROUND: MMN amplitudes are smaller in patients with schizophrenia than in matched healthy volunteers, and this neurophysiological index of deviance detection abnormalities has become one of the most widely replicated ERP findings. Recent studies have also reported smaller MMN amplitudes in help-seeking young people with functional impairment who meet the criteria for the ‘at risk mental state’ – attenuated psychosis like symptoms, or a family history of psychosis (e.g. Atkinson et al, Biological Psychiatry, 2012).

Conference Presentations
Physical Health Care Of Patients With First-Episode Psychosis: Prevalence Of Dyslipidemia And Weight Gain Aldanie Rho

Psychotropic medication has been associated with increase weight in people experiencing a first episode psychosis (FEP).Thus, the use of metabolic-neutral antipsychotics and regular monitoring have been encouraged. Objective: We aim to present monitoring practices, along with the prevalence of dyslipidemia and weight gain in a sample of 152 patients followed in a specialized early intervention service (PEPP-Montréal, Canada) between 2003 and 2011. Method: All participants completed their baseline metabolic panel.

Conference Presentations
Early detection and intervention evaluation for people at risk of psychosis (edie-2): a multisite randomised controlled trial of cognitive therapy for at risk mental states Anthony Morrison

Not Available

Conference Presentations
Outcomes of non-transitioned cases in a sample at ultra-high risk for psychosis: a medium to long-term follow-up study Ashleigh Lin

Background: Less than a third of individuals identified as ultra-high risk (UHR) for psychosis will develop frank psychotic disorder. Little is known about the outcomes of individuals at UHR who do not develop psychosis. This study aimed to examine non-psychotic diagnoses, comorbidities and attenuated psychotic symptoms at follow-up, as well as the course of non-psychotic disorders. Method: The sample comprised 226 individuals identified as UHR (at the PACE Clinic from 1993-2006) who had not transitioned to psychosis by follow-up (range = 2.4 to 14.1, median = 5.7 years).

Conference Presentations
Extending Specialized Early Intervention Service From 2 To 5 Years: A Randomized Controlled Trial Ashok Malla

The benefits of specialized early intervention services (SEIS) for psychotic disorders in the first two years have been reasonably well established. Recent evidence suggests that returning to regular care after two years of SEIS results in failure to sustain the benefits over the subsequent 3 years, achieved during SEIS tenure. Recently we have reported that a reduced intensity SEI services for an additional three years results in significantly better outcome (Norman et al 2011).

Conference Presentations
Social and role functioning in the prodromal phase of schizophrenia Barbara Cornblatt

Introduction: Research into prevention of schizophrenia has recently begun to focus on the often profound functional disability typically reported. Functional problems include poor social skills and an inability to carry-out age appropriate roles in the community (school or work). Increasing evidence suggests that social deficits, in particular, might be endophenotypes, directly reflecting underlying brain abnormalities. Methods: Functioning was evaluated for 128 clinical high risk (CHR) subjects and 52 help seeking controls (HSC).

Conference Presentations

Pages