IEPA 2012

Title Poster First Author Abstract or summary Type
The Impact Of Symptoms On Returning To Work Or School In First Episode Schizophrenia Patients Martin Lepage - Ventura

Introduction: Psychosocial intervention approaches such as supported employment have been successful in returning schizophrenia patients to competitive employment or school. A better understanding of the relationships among symptoms, employment, and school participation might help to maintain these forms of community functioning. Methods: Participants were schizophrenia patients who experienced a recent first episode (n=69). All patients received case management and either Individual Placement and Support or traditional vocational rehabilitation in an 18-month RCT.

Conference Presentations
Association of basal salivary cortisol secretion and impaired stress tolerance in two clinical high risk cohorts Cheryl Corcoran

Introduction: Stress sensitivity and HPA axis activity may be relevant to the development and expression of psychotic disorders. Salivary cortisol secretion is an easily assayed and valid marker of HPA axis activity. Methods: Two separate cohorts (N ~30) of clinical high risk patients were similarly ascertained (SIPS/SOPS) in the NY metropolitan area (RAP, COPE) and assayed for basal salivary cortisol.

Conference Presentations
Suicidality During The First Year Of Early Intervention Chris Jackson

Introduction: The number of people who kill themselves, think about killing themselves or deliberately harm themselves (DSH) following a first episode of psychosis remains stubbornly high (Pompili et al, 2011). Less is known about who is at risk of such suicidality and the role that EI services play in reducing it.

Conference Presentations
The Effects Of Cognitive Training On Neurocognitive Systems In Individuals At Clinical High Risk Christine Hooker

Individuals at clinical high risk (CHR) for psychosis have neural abnormalities and associated cognitive deficits that prospectively predict conversion to psychosis. This study investigated whether cognitive training in CHR participants would restore neural systems, enhance cognitive skills, and ultimately improve functional outcome. CHR participants completed behavioral and neural assessments before and after 40 hours/8 weeks of computer-based cognitive and social cognitive training.

Conference Presentations
Reduced Electrophysiological Response To Pleasant Images In Young Schizophrenia-Spectrum Patients: Association With Future Cannabis Use Clifford Cassidy

Background: multiple lines of evidence point to reward system dysfunction in schizophrenia-spectrum disorders (SSD) and substance-use disorders but there has been a lack of neurobiological research to test if blunted response to naturally reinforcing stimuli promotes substance use in SSD. Method: Response to emotional images and to visual cannabis cues was assessed in young SSD patients with (n = 20) and without (n = 12) cannabis use and controls with (n = 19) and without (n = 11) cannabis use.

Conference Presentations
Symptom Dimensions In Early Psychosis: Examining The Unique Contributions Of Depression And Anxiety On Functional Outcomes Daniel Fulford

Functional impairment is a defining feature of psychotic disorders and usually appears well before their onset. Negative symptoms play a prominent role in impaired functioning in schizophrenia and those at clinical-high-risk (CHR) for psychosis.

Conference Presentations
Biomarkers of conversion to psychosis in youth at elevated clinical risk Tyrone Cannon

At risk youth who develop psychosis show a substantial decrease in gray matter density in particular regions of the cerebral cortex during the year prior to onset, compared with age- and gender-matched healthy individuals and with at risk youth who do not develop psychotic disorders. Peri-onset changes in white matter integrity, brain physiology, and brain metabolite distribution appear to parallel the gray matter reductions.

Conference Presentations
Understanding, preventing, and addressing delayed social recovery problems in early psychosis David Fowler - Hodgekins

Not Available

Conference Presentations
Reducing DUP in Amsterdam: results from the top trial Don Linszen

Background: International early detection programs aiming to reduce the duration of untreated psychosis (DUP) show diverging effects resulting in identifying patients with shorter DUP, no effect and a long DUP. Methods: To examine the effects on the DUP for first-episode patients in Amsterdam as catchment area through the introduction of an early detection program (TOP), compared with historical cohorts in Amsterdam and Rotterdam without a TOP program.

Conference Presentations
Essential Evidence-Based Components Of First Episode Psychosis Services Donald Addington

Objective: The purpose of this study was to identify essential evidence-based components for First Episode Psychosis Services (FEPS). Methods: The study was conducted in two stages: In the first stage we conducted a systematic review of both peer reviewed and grey literature covering the period 2005 to 2010. Databases searched included Medline, PsycINFO and Embase. In the second phase we used a consensus-building technique, the Delphi, with an international panel of 28 experts.

Conference Presentations

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