IEPA 2012

Title Poster First Author Abstract or summary Type
The impact of long-acting injectable vs. oral risperidone on cognition and work functioning after an initial psychotic episode: the critical role of early medication adherence Keith Nuechterlein

Background: Cognitive deficits are a critical target for attempts to improve everyday functioning in schizophrenia. Although most studies have shown only modest effects of second-generation antipsychotic medications on cognitive deficits, they have typically focused on chronic phases of schizophrenia without considering medication adherence. Method: A 12-month, open-label, randomized controlled trial of long-acting injectable risperidone (RLAI) vs. oral risperidone is focusing on the impact of medication adherence after an initial episode of schizophrenia.

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